Comparative pathogenesis of Mycobacterium marinum and Mycobacterium tuberculosis
نویسندگان
چکیده
منابع مشابه
Comparative pathogenesis of Mycobacterium marinum and Mycobacterium tuberculosis.
A thorough understanding of Mycobacterium tuberculosis pathogenesis in humans has been elusive in part because of imperfect surrogate laboratory hosts, each with its own idiosyncrasies. Mycobacterium marinum is the closest genetic relative of the M. tuberculosis complex and is a natural pathogen of ectotherms. In this review, we present evidence that the similar genetic programmes of M. marinum...
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PURPOSE The aim of the present study was to investigate the immune response induced by Mycobacterium marinum infection in vitro and the potential of M. marinum as an immunotherapy for M. tuberculosis infection. METHODS The potential human immune response to certain bacillus infections was investigated in an immune cell-bacillus coculture system in vitro. As a potential novel immunotherapy, M....
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1. Ashford RW, Crewe W. The parasites of Homo sapiens: an annotated checklist of the protozoa, helminths and arthropods for which we are home. London: Taylor and Francis; 2003. 2. Haydon DT, Cleaveland S, Taylor LH, Laurenson MK. Identifying reservoirs of infection: a conceptual and practical challenge. Emerg Infect Dis 2002;8:1468–73. 3. Ashford RW. What it takes to be a reservoir host. Belgia...
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Previous studies of the 16S rRNA genes from Mycobacterium ulcerans and Mycobacterium marinum have suggested a very close genetic relationship between these species (99.6% identity). However, these organisms are phenotypically distinct and cause diseases with very different pathologies. To investigate this apparent paradox, we compared 3,306 nucleotides from the partial sequences of eight housek...
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Mycobacterium marinum, a ubiquitous pathogen of fish and amphibia, is a near relative of Mycobacterium tuberculosis, the etiologic agent of tuberculosis in humans. The genome of the M strain of M. marinum comprises a 6,636,827-bp circular chromosome with 5424 CDS, 10 prophages, and a 23-kb mercury-resistance plasmid. Prominent features are the very large number of genes (57) encoding polyketide...
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ژورنال
عنوان ژورنال: Cellular Microbiology
سال: 2008
ISSN: 1462-5814,1462-5822
DOI: 10.1111/j.1462-5822.2008.01133.x